منابع مشابه
Mathematical model of pulsed immunotherapy for superficial bladder cancer.
We present a theoretical study of superficial bladder cancer growth and its treatment via pulsed immunotherapy with Bacillus Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis. BCG pulsed immunotherapy is a clinically established procedure for the treatment of superficial bladder cancer. In this paper, periodic BCG instillations are modeled using impulsive differential equations...
متن کاملMathematical model for G-CSF administration after chemotherapy.
Granulocyte-colony stimulating factor (G-CSF) is used clinically for treating chemotherapy-induced neutropenia (low neutrophil levels). Here we present a delay differential equation model for the regulation of neutrophil production that accounts for the effects of G-CSF. Using a combination of analysis and numerical simulations, we use this model to study the effects of delaying G-CSF treatment...
متن کاملA Mathematical Model for Flood Protection
Many regions in the world are protected against flooding by a dike, which may be either natural or artificial. We deal with a model for finding the optimal heights of such a dike in the future. It minimizes the sum of the investments costs for upgrading the dike in the future and the expected costs due to flooding. The model is highly nonlinear, nonconvex, and infinite-dimensional. Despite this...
متن کاملMathematical Modelling and Analysis of the Tumor Treatment Regimens with Pulsed Immunotherapy and Chemotherapy
To begin with, in this paper, single immunotherapy, single chemotherapy, and mixed treatment are discussed, and sufficient conditions under which tumor cells will be eliminated ultimately are obtained. We analyze the impacts of the least effective concentration and the half-life of the drug on therapeutic results and then find that increasing the least effective concentration or extending the h...
متن کاملMathematical Models of Chemotherapy
Suppose one injects a drug into an animal. What is the time course of the drug concentration in the blood and in the various organs of the body? Although preliminary attempts to set up mathematical models of this problem were made by Teorell [1], [2] and models of certain special cases have been considered by von Schrotter [3], Smith and Morales [4], and Morales and Smith [5], [6], it continues...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ITM Web of Conferences
سال: 2015
ISSN: 2271-2097
DOI: 10.1051/itmconf/20150401004